Nice to meet you

My work spans from first-in-human testing of novel therapeutics to their application in patients with complex diseases. As an internationally recognized leader in polypharmacy, drug safety, and medicines optimization, I am dedicated to delivering better and safer medications for individuals living with multimorbidity.

My clinical expertise extends to leading outpatient clinics, inpatient reviews, and multidisciplinary team meetings for adults with complex multimorbidity and polypharmacy.

Passionate about advancing healthcare through research and collaboration, I am committed to optimizing medication use and improving patient outcomes on a national and international scale.

Education & Training Offerings

Polypharmacy & Multimorbidity Management

Understanding drug interactions and disease progression in complex patients.

Medicines Optimization & Deprescribing

Identifying when medication harms outweigh benefits.

AI & Machine Learning in Clinical Decision-Making

Exploring how AI-driven insights enhance prescribing and risk prediction.

Experimental Therapeutics & Drug Development

Understanding early-phase clinical trials and novel therapies.

Research & Innovations

AI-driven prescribing optimization

Identifying disease and prescribing trajectories in people with complex care needs. Visit

Health record analytics

Using machine learning to predict risks and improve patient safety.

Clinical & Leadership Roles

Deputy Director, NIHR Clinical Research Facility

Supporting early-phase clinical trials and precision medicine research.

Professor of Clinical Pharmacology & Therapeutics

Managing complex multimorbidity cases, inpatient reviews, and multidisciplinary team meetings.

Senior Investigator, AGILE Trial

Co-leading UK’s only government-funded early-phase COVID-19 therapeutic trial. Visit

Co-Director -TherEx

Innovating therapies for complex diseases with a particular focus on infection therapeutics

Chief Investigator

High-Dose Nitazoxanide Repurposing for COVID-19 – Ensuring low-cost global solutions through Unitaid-funded research.

Co-Chair

INational Polypharmacy Services Consortium (PPSC) – Developing an integrated, multidisciplinary approach to polypharmacy management.

Co-Director of NIHR

Cheshire & Mersey Commercial Research Delivery Centre

DynAIRx

DynAIRx (Artificial Intelligence for dynamic prescribing optimisation and care integration in multimorbidity) aims to develop new, easy to use, artificial intelligence (AI) tools that support General Practitioners (GPs) and pharmacists to find patients living with multimorbidity (two or more long-term health conditions) who might be offered a better combination of medicines.

Podcasts

The trials and tribulations of a Clinical Pharmacologist
orange and white plastic bottle on white textile
orange and white plastic bottle on white textile
a computer circuit board with a brain on it
a computer circuit board with a brain on it
Managing Complexities
DynAIRx

Key Publications & Academic Contributions

Walker LE, et al. AI for dynamic prescribing optimization and care integration in multimorbidity. J Multimorb Comorb, 2022.

Kuan V, Denaxas S, Walker LE, et al. Identifying and visualizing multimorbidity patterns in NHS patients. Lancet Digital Health, 2023.

Abuzour AS, Walker LE, et al. Barriers to structured medication reviews in primary care: The DynAIRx Study. PLoS ONE, 2024.

Braithwaite E, Todd OM, Walker LE, et al. Interventions for reducing anticholinergic medication burden in older adults. Age and Ageing, 2023.

Walker LE, Fitzgerald R, et al. An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: A COVID-19 Antiviral Candidate. Clin Pharmacol Ther, 2022.

Trying my best to learn

University of Liverpool

Post-Graduate Certificate Academic Practice (PGCAP)
2020

University of Liverpool

PhD Pharmacology
2015

University of Liverpool

M.B., Ch. B (Hons)

2007

Education

Membership

Sponsorship Committee

Member
2023

Cure C ethics committee

Member
2022

Athena Swan Committee

Member

2023

Have any questions?

If you have any questions about the therapies, feel free to contact us.